The cervical degenerative spine market has changed over the years. At the beginning of the 90s, cervical plates were the gold standard for degenerative indications. Later, in that decade, interbody cages appeared for the first time. They provided primary fixation solving the problem of bone graft resorption. However, they have to be used in conjunction with a cervical plate.Recently, stand-alone cages have been launched and have changed the game. Due to their ease and speed of use, most companies have included them in their portfolio. Now, there are more than 100 stand-alone cervical cages in the market. Undoubtedly, they have become the implant of choice in cervical degenerative surgery.
Do stand-alone spacers have improved operative characteristics and postoperative outcomes in ACDF cohorts when compared to cage and plate constructs?
According to many studies , including the following “The efficacy of anchored stand-alone spacers in comparison to conventional cage and plate in anterior cervical discectomy and fusion surgery: A meta-analysis of randomised controlled trials for clinical and radiological outcomes” it is highlighted the efficacy of stand-alone spacers for the management of primarily cervical spondylitic disease for both single-level and multi-level pathology.
How is the market?
Understanding stand-alone cages in isolation misses the bigger picture: the overall cervical interbody fusion cage segment and spinal fusion device market are growing steadily, driven by aging populations, rising incidence of degenerative spinal conditions, and increased adoption of minimally invasive techniques.The global cervical interbody fusion cages market was valued at approximately USD 948 million in 2024 and is projected to reach around USD 1.27 billion by 2032, growing at roughly 4.3% CAGR over that period. This growth is fueled by the Stand-alone cages:
Why the cervical stand-alone cages market grows?
- First, because it is a simple procedure: Traditionally, in order to hold an IBD in place, the surgeon had to use a supplemental fixation plate to help. These newstand-alone design by utilizing two screws to help secure the IBD in its functional position, eliminates the need for a supplemental fixation plate making the procedure more easy and fast to implement.
- Second, because the US spinal implant market is a mature market with its largest product segments — traditional anterior cervical plating and posterior thoracolumbar pedicle screw fixation — featuring largely commoditized products and a lack of product innovation”.Steady pricing decreases are expected in most segments of the spinal implant market through 2024.Fortunately, shifts in procedure and product mix to premium-priced plate/cage hybrid devices with integrated screw fixation, (stand-alone cages) will help offset declining unit prices.
Today we put at your disposal the list of most of the implants that are on the market and even some that are no longer there. We hope this information is useful to you.
No Single “Best” Cage — Only Defined Archetypes
With so many products in play, the question isn’t which is the best stand-alone cage, but rather which design archetype delivers what you need. Leading examples from major players illustrate how the market has differentiated:
- Zero-profile designs: minimize anterior implant prominence and soft-tissue interaction while preserving familiar workflows.
Examples: AIS-C Stand-Alone System (Genesys Spine), ZERO-P (DePuy Synthes) - Integrated internal fixation: prioritize immediate mechanical stability by embedding screws or anchors directly into the cage.
Examples: AIS-C 3DP Stand-Alone Cage (Genesys Spine), Divergence (Medtronic), - Plate–spacer integrated systems: merge spacer and anterior plate concepts into a single implant, simplifying the procedure while retaining plate-like behavior.
Examples: Quasar™ Stand Alone ACIF System (GS Medical), COALITION (Globus Medical) - Porous / trabecular interfaces: focus on improving the bone–implant interface and secondary stability through enhanced osseointegration.
Examples: HEDRON IC (Globus Medical), Carsten Trabecular Cage (Normmed) - Simple mechanical or blade-based designs: emphasize straightforward technique, functional reliability, and cost-efficiency.
Examples: Polar-B (Normmed), ACIFBOX (Spineway)
How many Stand Alone cages compete in this market?
We found at least 110 products with different designs and materials. If you want to know more about them, please visit our ACIF Stand-Alone section:https://thespinemarketgroup.com/category/acif/stand-alone/
To watch video animations from many of the following products, please visit the following Youtube Link: Stand-Alone Cervical Cages VIDEO ANIMATIONS

AIS -C 3D | AIS-C | Capri-Z | Carsten | Quasar | Eminent | Polar-B | Redmond | ACIFBOX Stand-Alone| ACIFBOX Blade
Featured:
- AIS-C 3DP Stand-Alone Cervical Cage (Genesys Spine)
- AIS-C Stand-Alone System (Genesys Spine)
- Capri-Z (Tsunami Medical)
- Carsten Trabicular Stand-Alone Cage (Normmed)
- Quasar™ Stand Alone ACIF System (GSMedical)
- Eminent Spine Cervical Cage (Eminent Spine)
- Polar-B Cervical Bladed Peek Cage (Normmed)
- Redmond Polymer Cervical Cage (A-Spine)
- ACIFBOX Stand Alone Cervical Cage (Spineway)
- ACIFBOX Cervical Cage with Blade (Spineway)
Cervical Stand-Alone Cages
- Alta System
- Align SA-C
- Aero-C
- ARION Expandable Bladed Cervical Cage
- Arcadius ®XP C Spinal System
- AVS® Anchor-C Cervical Cage
- Autoblock Anterior Cervical Cage
- A-CIFT™
- SoloFuse™
- Blackhawk™Cervical Spacer ChoiceSpine
- Blackhawk™ Ti Cervical Spacer ChoiceSpine
- CoRoent® Small Interlock™
- COALITION
- ClariVy Cervical IBF System
- C-Fix Peek
- Cedix-P Spacer
- COALITION MIS® SintrOS™
- Crea STAND-ALONE CERVICAL PEEK CAGE
- COALITION MIS™
- CHESAPEAKE® Cervical-Ti Stabilization System
- CAVUX Cervical Cage-L SA System
- C2C Cervical Titanium Spine System
- Ceres-C Stand-alone
- Cavetto- SA™ Ti
- C-CURVE™
- Dakota ACDF™ System
- Delta Anterior Cervical Plate And Cage Combination System
- Dolomite ACSS System
- Divergence
- Endoskeleton® TCS
- HiJAK AC
- Hive™ Standalone Cervical System
- HRCC®
- HEDRON IC™
- Hexanium ACIF cage
- Intervertebral cervical locking cage
- F3D C2 Stand Alone Cervical
- Idys®-C ZP 3DTi
- Irix-C™
- InterPlate™ IFD
- IN:C2 Cervical Cage
- Kentro SELF Standalone Cervical cage
- LorX ACIF Peek Cage
- L-ACIF
- LONESTAR® Cervical Stand Alone
- Monza
- Miraclus ACC
- Mecta-C Stand Alone Interbody Fusion
- Monet™ Anterior Cervical Fusion system
- MONET NITRO™ anterior cervical fusion system
- MINERVA
- NEXXT MATRIXX® Stand Alone Cervical System
- Optio-C® Anterior Cervical System
- OVERFIX Cervical Cage
- ONIX
- Paramount® Anterior Cervical Cage
- Pegasus Anchored Cervical Interbody
- Pallas Low Profile Anterior Cervical Cage
- PRO-LINK Ti Titanium Stand-Alone Cervical Spacer System
- Pro-less Cage
- PRO-LINK Stand-Alone cervical spacer
- PRORAY™ (PRODORTH)
- PROYSTER® (PRODORTH)
- PL-AGE® Anterior Cervical Fusion System
- PEEK Prevail®
- ReConnect Cage
- ROI-C
- Rig®-ZP (Zero Profile Cervical cage)
- Romero Self-Anchored Cervical Cage
- Red Ruby ACI
- SpineLinc Anterior Cervical Implant System
- SPIRA- C Integrated Interbody system
- STACC
- STALIF C FLX
- STALIF C-Ti™
- SABER C™ Cervical Fusion System
- SCARLET®AC-T
- SKATE, Cervical Plate Kit
- SPICCA-SP
- Solitaire™-C Cervical
- Siluette
- Shoreline® ACS
- T-lock Cervical Stand-alone Cage (BAUI)
- Tesera SC Stand-alone
- TRUSS CSTS-SA
- TOMCAT™ Cervical Spinal System
- TrellOss®-C SA Porous Ti Interbody System
- Titanopeek-C Stand Alone
- Vertu® Cervical Implant System
- Unicorn CS
- UniSpace® Stand-Alone C Cage
- VariLift®-C
- Vault C Anterior Cervical
- Velofix™ SA Cervical Cage
- Veyron-C System
- Walnut
- X-Zone System
- ZERO-P™ VA Stand Alone Spacer
- ZERO-PZ-LINK™ Cervical
- Zero-Profile Anterior Cervical Intervertebral Locking Plate And Cage Combination System
All video parts, images and documents related to the products are of the sole property of the different companies.All the information is for Educational purpose only! No copyright infringement intended.We encourage you to contact us if you have any comment, suggestion or if you want us to include/remove your videos, images or brochures. Please contact us: spinemarketgroup@gmail.com
