Modulus ALIF

• Modulus ALIF VIDEO ANIMATION

Benefits:

• Advanced Materials Science®: Adhering to the three core principles of Advanced Materials Science—Surface, Structure, and Imaging—NuVasive has pioneered design and manufacturing methods that combine the inherent benefits of porosity with the advantageous material properties of titanium to create implants intelligently designed for fusion.

• Porous surface designed to participate in fusion: Porosity elicits a significantly stronger osteogenic response at the cellular level compared to roughened or nano-roughened surfaces^2-5 on their own.Fully porous endplate design promotes new bone on-growth and in-growth,¹ demonstrating the greatest integration strength by 12 weeks compared to alternative implant materials.¹Microporous endplate architecture maximizes bone-to-implant contact, increasing expulsion resistance.⁶The increased surface area and wicking capability of the porous surface improves blood to implant contact compared with traditional interbody implants.

• Optimized lattice structure: Implants are designed with an optimized balance between strength and stiffness so as to minimize stress shielding⁷ and subsidence.⁸Modulus implants implement a proprietary design optimization methodology, generating a unique internal architecture for a desired effective modulus that is similar to bone.

• Enhanced imaging characteristics for visualization of fusion: Created with imaging clarity in mind, the proprietary implant design and manufacturing process allow enhanced visualization on a variety of imaging modalities.

About NuVasive

NuVasive, Inc. (NASDAQ: NUVA) is transforming spine surgery and beyond with minimally invasive, procedurally-integrated solutions designed to deliver reproducible and clinically-proven surgical outcomes. The Company’s portfolio includes access instruments, implantable hardware, biologics, software systems for surgical planning, navigation and imaging solutions, magnetically adjustable implant systems for spine and orthopedics, and intraoperative monitoring service offerings. With $962 million in revenues (2016), NuVasive has an approximate 2,300 person workforce in more than 40 countries serving surgeons, hospitals and patients. For more information, please visit www.nuvasive.com.