3D printed cellular titanium implants that feature 80% porous macro-, micro- and nanostructures, are designed to mimic cortical and cancellous bone, and facilitate fusion.
Features:
BONE-MIMICKING
Cellular design facilitates fusion and mimics the properties of
bone with macro-, micro- and nanostructures
- Macrostructure:
Surface roughness has been shown to have a beneficial
effect on cell differentiation and proliferation in in-vitro
studies of osteoblast-like cells cultured on similar roughened
titanium materials - Microstructure:
• In-vitro studies have reported greater osteoblastic differentiation
in human stem cells cultured on similar porous titanium
constructs compared to solid titanium surfaces9
• In-vivo studies with similar porous titanium materials show that
bony in-growth is increased at the 500-700 μm pore size range
compared to larger or smaller pores10-12
• The porosity of cancellous human bone is typically 50-90%13
• Based on this published science, CONDUIT™ Implants are
designed with 80% porosity and 700 μm pore size2,14 - Nanostructure:
• Similar titanium materials with nanoscale features have shown
in in-vitro studies to lead to increased osteoblast adhesion
when compared to conventional titanium materials15
• All CONDUIT Implants undergo acid etching and heat treatment
to promote micro- and nanoscale surface roughness
EXCELLENT VISUALIZATION
Ability to clearly visualize the cage intra- and post-operatively
on imaging modalities without interference 80% porosity:
• High radiographic visibility allows for better contouring,
endplate-implant contact evaluation and absence of
tantalum marker scattering intra- and post-operatively
• Clear visualization of the implant on X-Ray, absence of
scattering on CT Scan and diminished artifacts in MRI3
TARGETED MODULUS OF ELASTICITY
Modulus of Elasticity similar to cancellous bone
Proprietary 3D printing technology leads to cellular design that
offers Modulus of Elasticity of titanium similar to bone5
• Highly porous surface area and implant footprint variety
that allows for maximum endplate-implant contact
About DePuy Synthes
Founded 1895 in Warsaw, Indiana, by Revra DePuy, DePuy operates as a brand under the Johnson &Johnson Medical organization.On April 27, 2011, DePuy and Synthes agreed to a merger deal. The DePuy Synthes Companies offer the world’s most comprehensive portfolio of orthopaedic and neuro products and services for joint reconstruction, trauma, spine, sports medicine, neuro, cranio-maxillofacial, power tools and biomaterials. http://www.depuysynthes.com