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Top Six Spine Industry Milestones in 2025

December 20, 2025 By SPINEMarketGroup

In 2025, the spinal implants industry has experienced a year of significant strategic moves and major changes. Several companies have chosen to exit this business, either due to a lack of focus or because they see more profitable opportunities in other markets. Among all the transactions and restructurings, six events stand out as particularly important:

1. Stryker Sells U.S. Spinal Implants Business
In January, Stryker announced the sale of its U.S. spinal implants business to Viscogliosi Brothers, LLC, creating a new independent company called VB Spine, LLC. Plans are also underway to divest certain international operations, starting with France, pending regulatory approvals. VB Spine will serve as a strategic partner to Stryker, with exclusive access to the Mako Spine and Copilot platforms for spinal procedures.

2. Globus Medical Acquires Nevro Corp.
In February, Globus Medical finalized an all-cash acquisition of Nevro Corp., valued at approximately $250 million. The deal strengthens Globus’ position in musculoskeletal solutions and chronic pain management, while expanding its portfolio of innovative spinal devices.

3. Medtronic Acquires Nano Surface Technology from Nanovis
Also in February, Nanovis, a leader in nano surface technology that enhances biological fixation of orthopedic, dental, and spinal implants, sold certain technology assets and related intellectual property rights for Sites Medical’s OsteoSync™ titanium pads to Medtronic. This acquisition will help Medtronic develop the next generation of PEEK interbody fusion devices.

4. Companion Spine Acquires Paradigm Spine
In July, Companion Spine LLC acquired Paradigm Spine GmbH and the Coflex® and CoFix® implants from Xtant™ Medical, reinforcing its leadership in posterior dynamic stabilization and motion-preserving spine technologies. The deal will strengthen Companion Spine’s international platform and allow a focused approach to treating lumbar spinal stenosis and degenerative disc disease, with completion expected in Q3 2025.

5. Highridge Medical Expands Its Portfolio of Expandable Implants
In September, Highridge Medical acquired the FlareHawk® and Toro™ expandable interbody fusion systems, along with the LineSider® pedicle screw system from Accelus. The transaction integrates proprietary Adaptive Geometry® designs, providing advanced solutions for hospitals and ambulatory surgery centers, and demonstrates Highridge’s continued commitment to innovation and R&D.

6. Johnson & Johnson Separates Its Orthopedics Business
In October, Johnson & Johnson announced that its orthopedics business will spin off as DePuy Synthes, becoming the world’s largest independent orthopedics company. This reorganization allows J&J to focus on higher-growth, higher-margin MedTech markets, while DePuy Synthes will lead key global implant and orthopedic solution categories.

Industry Takeaways – Spinal Implants 2025

  • Industry Consolidation: Large companies are selling parts of their spinal implant businesses, creating opportunities for smaller, more specialized firms.
  • Innovation as a Priority: Acquisitions like Medtronic’s purchase of Nanovis highlight the focus on next-generation implants and improving patient outcomes.
  • Strategic Deals Reshape the Market: Transactions such as Globus/Nevro, Companion Spine/Paradigm, and Highridge/Accelus show how companies are strengthening portfolios and expanding internationally.
  • Growing Specialization: Spin-offs like VB Spine and DePuy Synthes reflect a trend toward creating companies dedicated exclusively to spinal care or orthopedics.

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Filed Under: ARTICLES, NEWS Tagged With: 2025

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