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New Multicenter Study Published in Healthcare (MDPI) Highlights Clinical Outcomes of SiLO TFX™ for Chronic SI Joint Pain

July 2, 2025 By SPINEMarketGroup

A newly published multicenter study in the journal Healthcare MDPI brings promising data on the use of the SiLO TFX™ posterior sacroiliac joint fusion system for patients suffering from chronic sacroiliac joint (SIJ) dysfunction. The article presents clinical and functional outcomes from multiple treatment centers and contributes valuable evidence to the growing interest in minimally invasive approaches for SI joint pain.

  • SiLO TFX Surgical Technique VIDEO ANIMATION

Clinical Study Summary

The study presents a retrospective analysis of 42 patients who underwent SI joint fusion using the SiLO TFX™ system between March 2023 and February 2024. With a mean age of 60 years and 71% female participation, the patients had all failed conservative therapies prior to surgery. Outcomes were evaluated at 12 months using standard clinical measures: the Oswestry Disability Index (ODI) for function and the Numeric Rating Scale (NRS) for pain.

Results showed a significant and clinically meaningful improvement. The mean ODI decreased from 33 to 17 points, with an average improvement of 16 points (p < 0.0001), and more than half of patients (52%) achieved a reduction of at least 15 points. Pain scores on the NRS dropped from 7.1 to 2.9, with a mean reduction of 4.2 points (p < 0.0001). Among patients with more severe baseline symptoms (ODI ≥ 30 and VAS ≥ 50), the results were even more pronounced: average ODI improvement was over 23 points, and 78% reached the threshold for clinically significant functional recovery, while nearly 89% reported a pain reduction of 2 points or more.

Importantly, no serious adverse events were reported—no infections, neurological complications, or implant failures—highlighting the safety of the technique. The study concludes that the SiLO TFX™ system offers a safe, effective, and well-tolerated solution for patients with chronic SI joint pain, especially those who have not benefited from conservative treatments.

About the SiLO TFX™ System

The SiLO TFX™ is a posterior, transfixing sacroiliac joint fusion system developed by Aurora Spine. Designed for minimally invasive implantation, the system uses a titanium cannulated core implant with four graft windows that allow for bone graft packing and enhanced fusion potential. Fixation is achieved through both sacral and iliac screws, providing tri-point stability across the joint. Unlike lateral or transiliac fusion techniques, SiLO TFX™ preserves more bone and may reduce surgical trauma and recovery time. Preclinical biomechanical studies have demonstrated the device’s superior joint stabilization under load, with significant reductions in joint motion and excellent resistance to migration. The SiLO TFX™ system is an innovative solution for patients needing SI joint fusion, combining mechanical performance with a minimally invasive, tissue-sparing approach.

About Aurora Spine

Aurora Spine is focused on bringing new solutions to the spinal implant market through a series of innovative, minimally invasive, regenerative spinal implant technologies. Additional information can be accessed at www.aurora-spine.com.

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Filed Under: NEWS Tagged With: 2025

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