Global artificial disc market is predicted to attain revenue of $3.3 billion by 2024, according to a market research report published by P&S Intelligence.
Cervical discs are expected to generate revenue of $2,479.6 million by 2024. According to iData Research, Inc. , the Cervical Artificial Disc Segment is expected to Comprise Nearly €57 million of the Overall Europe Motion Preservation Market by 2023.Growth of the artificial disc market is fueled by cervical artificial discs (CADs) due to their simpler approach, favorable clinical results and lower average selling prices (ASPs), along with a favorable reimbursement environment.
In the past, when the market was growing, most of the companies have these devices included in their portfolio.At that time we counted more than 50 different Cervical Artificial Discs as you can check in our ADR section. Some of them have already disappeared.
Today, we want to highlight the 11 Cervical Artificial Discs that we consider to be the most relevant ones. We would like to thank Deepak Pandey (because we missed the Freedom Cervical) and Christian Mainusch (for FH ESP).
1.- PRODISC C Vivo | Centinel Spine
Although Centinel Spine, have 3 different Prodisc C versions (Prodisc C, Vivo, Nova), we have included only this one.
The Prodisc C Vivo consists of a cranial and a caudal implant-endplate. The inlay is made of ultra-high molecular polyethylene. The ball and socket joint principle allows a physiological range of motion with regard to flexion/extension, rotation and lateral bending.
The prosthesis is implanted by a standard anterior access of the cervical spine. After removal of the disc, the size is determined by the trial implants. The aim is to select the best possible anatomical fit, i.e. an implant with the largest contact surface and the smallest height, in order to replace the natural intervertebral disc optimally.
Under image intensifier control, the implant is inserted by slight hammering.
2.-MOVE C | NGMedical
MOVE-C combines the features of a second generation disc prosthesis with the simple implantation technique of a cervical cage. The prosthesis offers physiological motion in all 6 planes including axial damping with progressive resistance to motion. Furthermore, MOVE-C is the first prosthesis with additively manufactured titanium endplates and avoids the use of PE.
Features:
- Unique Function & Simplicity
- MOVE-C enables physiological movement in all 6 degrees of freedom with axial damping and progressive increase in resistance. Simple and safe without a separate core.
- Physiological ROM in 6 directions with defined neutral zone
- Pre-mounted on implant holder
- Built-in lordosis
3.-ACTIF C |BBRAUN
Activ C is the cervical disc prosthesis for a motion preserving treatment of degenerative cervical disc disease. It is indicated for light to moderate degeneration of cervical disc with light to moderate changes of the disc, vertebral endplates, osteophytes and/or with fresh herniated disc.
The specific motion pattern, physiological center of rotation and the shape of prosthesis-plates ensure the best possible adaption to natural anatomy and biomechanics of the patient for a fast reduction/elimination of pain/neurological deficits and a longterm preservation of motion patterns and the protection of adjacent levels.
Advantages:
1.- Safe anchorage and prevention of vertebral body splitting by the combination of spikes and keel and specific technique of keel preparation.
2.- Improved primary stability and fast ingrowth fo bone cells through Plasmapore® coating
3.- Fast and safe bonding between bone and prosthesis surface
4.- Natural motion pattern through shape and type of inlay/prosthesis, analogy between motion patterns of facet joints and prothesis
5.- Good conformity with anatomy of vertebral body and improved primary stability by anatomical shape of prosthesis plates
6.- Safe and easy application in cases with narrow disc space through small height of prosthesis
7.- Flexible use in different grades of degeneration through specific designs
8.- Low risk of complication by safe materials and simple surgical technique
Properties
- Primary stability by a combination of spikes and keel
- Secondary and primary stability by Plasmapore® coating
- Radius of inlay adapted to mean values of normal distribution of anatomy
- Anatomical shape of prosthesis plates
- Smallest height with 5 mm
- Different designs for indications with light to moderate degeneration
- No risk for split of vertebral bodies
- Solid materials (Cobalt-Chrome-Molybden/high molecular Polyethylene)
- Easy preparation for keel
- Easy handling
4.-M6-C™ | Orthofix
The M6-C™ artificial cervical disc technology provides an alternative to spinal fusion and is designed to restore natural and physiologic motion. Preserving motion with the M6-C disc provides an opportunity to restore biomechanical function at the treated level after native disc removal, as well as the possibility to reduce subsequent degeneration of adjacent segments. With its innovative single piece design for ease of implantation and ability to replicate a natural disc’s motion, the M6-C artificial cervical disc is the natural choice. Visit www.M6disc.com for more information.
Features:
- Sheath:
- Viscoelastic polymer (PCU) designed to minimize tissue in-growth and debris migrationFixation:
- Titanium alloy endplates with low profile tri-fin design provides acute fixation to the superior and inferior vertebral bodiesTitanium Plasma Spray (TPS) coating intended to promote bone growth, providing long-term stability
- Artificial Nucleus:
- Viscoelastic polymer (PCU) designed to stimulate native nucleus structure
- In combination with the artificial annulus, allows physiologic axial compression
- Retained between endplates by fiber annulus matrix
- Artificial Annulus:
- Ultra High Molecular Weight Polyethylene (UHMWPE) fiber matrix designed to simulate native annular structure
- In combination with the artificial nucleus, allows controlled motion in all planes and axes of rotation
- Robust fiber matrix with multiple fiber layers similar to native annulus
5.-Simplify Cervical Disc | Nuvasive
Simplify Cervical Disc, an MRI compatible disc, is designed and manufactured by Simplify Medical, a San Francisco Bay Area-based medical device company designing, developing and clinically testing the most advanced cervical artificial disc for use in the spine.Simplify is designed to preserve motion in patients suffering from symptomatic cervical disc disease (SCDD)Simplify eliminates the need for CT/Myelogram and CT imaging in follow up clinical exams.
Key Benefits:
- Simplify – MRI Compatible Artificial Disc
- Simplify is the only cervical artificial disc composed primarily of MRI friendly materials
- Simplify eliminates the need for radiation-intensive CT/Myelograms
- Simplify PEEK endplates are compliant
- Simplify PEEK-on-ceramic articulation is designed for low levels of wear to optimize long-term durability
- Simplify Benefits Smaller Patients and Women
- Simplify provides low height implant options for patients with smaller cervical disc spaces, for whom larger implant options are not suitable
- Simplify may benefit patients with smaller anatomy requiring cervical arthroplasty, expanding the number of patients eligible for treatment
- Simplify disc heights ( 5 – 6mm) and footprint sizes are designed to closely match patients’ anatomies
6.-Mobi-C | Zimmer Biomet
The Mobi-C Cervical Disc has been designed for cervical disc replacement to restore segmental motion and disc height. The components of Mobi-C include superior and inferior cobalt chromium molybdenum alloy endplates coated with plasma sprayed titanium and hydroxyapatite coating, and a polyethylene mobile bearing insert. The controlled mobility of the patented mobile core is the foundation of Mobi-C, encouraging height restoration and respect of the instantaneous axis of rotation for a return to physiological mobility of the spinal segment.
- Mobi C.One level-Brochure. Zimmer Biomet (LDR).pdf
- Mobi C.Two levels-Brochure.Zimmer Biomet (LDR).pdf
- Mobi C-One level-SGT.Zimmer Biomet (LDR).pdf
- Mobi C-Two level-SGT.Zimmer Biomet (LDR).pdf
- Mobi C VIDEO Animation
Features:
- Patented Mobile Bearing Technology
- Controlled mobility is provided with a mobile core that can translate up to 1mm on the inferior endplate
- Designed to facilitate both independent and coupled motions similar to natural cervical spine motion
- Bone Sparing Technology
- No bone chiseling, no invasive keels or screws required
- Intact bony endplates provide a preserved surface that is ideal for two-level implantation
- Intraoperative flexibility to optimize implant positioning
- Ease of Insertion
- Mobi-C provides one step insertion, with no additional exposure or operative steps required for keel or screw placement
- Mobi-C comes preassembled on a disposable radiolucent PEEK cartridge
7.- SECURE®-C | Globus Medical
The SECURE-C® Cervical Artificial Disc is a motion-sparing technology designed as an alternative to fusion. Through its unique selectively constrained design, SECURE-C® is designed to allow up to ±15º motion in flexion-extension and up to ±10º motion in lateral bending. The design is intended to allow unlimited axial rotation and to permit sagittal plane translation of ±1.25mm. Clinical study data demonstrates statistical superiority of SECURE-C® to ACDF in terms of overall success and patient satisfaction at 84 months postoperative.
Features:
- Motion Preservation
- SECURE-C® is designed to allow motion through its novel selectively constrained design, which provides articulation and sagittal plane translation.
- Optimal Fit
- The device is available in two sagittal profiles (0º & 6º lordosis) and a range of footprints and heights to fit the disc space.
- Streamlined Technique
- Exclusive instruments allow for device placement in three basic steps: Trial – Chisel – Insert
8.- CP-ESP | FH Orthopedics
The ESP prosthetic disc is the result of 10 years of collaborative research work at the Hôpital Pitié Salpêtrière in Paris, the French Atomic Energy Commission (CEA) and the Université Paris VI, and was driven by the Oséo Innovation contest in France.
The disc consists of two titanium alloy end plates separated by a deformable core intended to allow natural disc movements.
The ESP prosthetic disc restores the mechanical properties of the intervertebral disc and in particular, its shock-absorbing properties.
The CP ESP prosthesis helps to reduce pain and to achieve near-normal disc function.
The stiffness of the deformable core resembles that of the native intervertebral discs. This stiffness is due to a flexible polycarbonate urethane cushion. This flexible cushion, attached to the two metal endplates, provides the disc with its shock-absorbing function and limits the release of particles into the body and the calcification of deformable parts.
Features:
- Heights from 5mm to 7mm
- Benefits from over 10 years of development
- 6 degrees of freedom
- Adaptive center of rotation
- No surface bearing for increased lifetime
- Improved stability
- Shock absorbing
- Six degrees of freedom restore your “natural” mobility
- Lateral flexion
- Vertical translation
- Lateral translation
- Flexion/extension
- Anterior-posterior translation
- Axial rotation
9.-BAGUERA C | SpineArt
Baguera C is the Spineart®’s cervical disc prosthesis. It is easily implanted with its compact set of high quality instrumentation.
Benefits:
- GUIDED MOBILE NUCLEUS
The guided mobile PE nucleus is designed to prevent excessive constraints on the facet joints. It allows 6 degrees of freedom. - ANATOMICAL DESIGN
The sloping anatomical design of the plates optimizes the fit between the device and the disc space, and maximizes the endplate coverage. - REDUCED MRI ARTIFACT
The DIAMOLITH® coated titanium plates reduce artifacts under MRI for a better postoperative control. - RADIOLUCENT HOLDER
The radiolucent holder allows for both the verification of the anterior position of the device and confirmation of the fitting accuracy. Thanks to this holder, the device is delivered pre-assembled for better handling.
10.- Freedom® Cervical Disc (FCD) | Axiomed
The FCD is intended to replace degenerated lumbar or cervical discs. The FCD polymer core is designed to provide the kind of stiffness similar to that found in healthy human discs. Like human discs, the core is viscoelastic, which means they respond to different loads and loading rates the way a human spine does.
The material characteristics of the polymer used in all Freedom® Discs, in combination with their design, provide both stability and three-dimensional motion that biomechanical testing has shown functions within the natural biomechanics of the spine. The Freedom® Lumbar and Cervical Discs are designed to withstand the forces and wear characterized by decades of use as an implant in relatively young patients. (Freedom® Cervical Disc not available in the US).
Benefits:
- Responds to loading like the human spine
- Withstands the forces and wear of decades of use
- Moves in three dimensions like the human spine
- Polymer core has flexibility and stiffness that mimics a healthy human disc
11.- Rotaio Cervical disc | Signus
Implantable like a cage – moves like a disc
ROTAIO®* has the aim to replicate the natural movement of a healthy disc. The solution: a variable centre of rotation,enabling physiological facet-guided movement. This ensures that the emphasis is not merely on maintaining movement, but in particular on the quality of movement of a natural disc.
ROTAIO®is implanted by the ‘gold-standard’ Smith-Robinson technique as a single component without additional preparative surgical steps. ROTAIO®can therefore be described in a single phrase: Implantable like a cage – moves like a disc.ROTAIO®offers not only rotation, flexion/extension and lateral flexion, but also the possibility of uncoupled translation. In this way, ROTAIO®optimally reproduces the natural centre of rotation and thereby provides physiological, facet-guided, segmental movement. ROTAIO®is implanted «in one piece» with no additional preparative steps.
*no fda
Special ROTAIO®features:
Safety oriented prosthesis design
- One-piece prosthesis design for safe handling:
Implantable like a cage
- Rectangular geometry with large contact surface area with the vertebral body – for secure implant seating and reduced risk of subsidence
Tested mechanics1
- A comprehensive series of cyclic, dynamic and static tests going beyond the studies required for marketing authorisation
Increased roughness2 in conjunction with proven SIGNUS toothed cage design
- Secure anchoring in the bone owing to high primary stability
- No keel preparation required
- Reduced risk of implant migration
Physiological mobility
- Range of motion is defined by anatomical structures and not by the disc prosthesis
- Posteriorly-accentuated implant design
- Perfectly adapted to the natural anatomy
- Variable centre of rotation corresponds to the natural centre of motion of the cervical spine
- Controlled translation uncoupled from rotation
- Allows for facet-guided movement, with no gaping joints
Pre-mounted, in sterile packaging
- No assembly necessary, ready for use